منابع مشابه
Small nerve fiber involvement in patients referred for fibromyalgia.
INTRODUCTION Fibromyalgia (FM) is a chronic syndrome characterized by widespread pain often accompanied by other symptoms suggestive of neuropathic pain. We evaluated patients for small fiber neuropathy (SFN) who were referred for fibromyalgia (FM). METHODS We studied 20 consecutive subjects with primary FM. Patients underwent neurological examination, nerve conduction studies, and skin biops...
متن کاملSmall Nerve Fiber Pathology in Critical Illness
BACKGROUND Degeneration of intraepidermal nerve fibers (IENF) is a hallmark of small fiber neuropathy of different etiology, whose clinical picture is dominated by neuropathic pain. It is unknown if critical illness can affect IENF. METHODS We enrolled 14 adult neurocritical care patients with prolonged intensive care unit (ICU) stay and artificial ventilation (≥ 3 days), and no previous hist...
متن کاملPMP22 expression in dermal nerve myelin from patients with CMT1A.
Charcot-Marie-Tooth disease type 1A (CMT1A) is caused by a 1.4 Mb duplication on chromosome 17p11.2, which contains the peripheral myelin protein-22 (PMP22) gene. Increased levels of PMP22 in compact myelin of peripheral nerves have been demonstrated and presumed to cause the phenotype of CMT1A. The objective of the present study was to determine whether an extra copy of the PMP22 gene in CMT1A...
متن کاملEDITORIAL REVIEW Small fiber involvement in peripheral neuropathies
Introduction Small fiber involvement in different patterns of peripheral neuropathy has stirred much interest during the past few years due to the role played by these fibers in pain perception and the availability of new techniques of skin biopsy that permit the study of nerve endings [1]. The use of protein gene product 9.5 (PGP 9.5) as a panaxonal marker in skin biopsies has led to identific...
متن کاملSmall-diameter nerve fiber neuropathy in systemic lupus erythematosus.
BACKGROUND Systemic lupus erythematosus (SLE) is an inflammatory, autoimmune, multiorgan disease often involving the central and peripheral nervous systems. OBJECTIVE To determine whether there is a selective small-diameter nerve fiber neuropathy in patients with SLE. DESIGN Cross-sectional study. SETTING Stavanger University Hospital, Stavanger, Norway. Patients Sixty patients with SLE, ...
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ژورنال
عنوان ژورنال: Neurology
سال: 2014
ISSN: 0028-3878,1526-632X
DOI: 10.1212/wnl.0000000000001188